ArticleJournal of medical case reports2026
Elevated beta-human chorionic gonadotropin levels in a patient with end-stage renal disease awaiting kidney transplantation: a case report.
Article in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundSerum beta-human chorionic gonadotropin is routinely measured as a pregnancy marker in women of reproductive age prior to diagnostic and therapeutic interventions. Although a positive result commonly indicates pregnancy, false-positive values may occur, particularly in women with chronic kidney disease due to impaired renal clearance. CASE PRESENTATION: We report the case of a 23-year-old Iranian woman with end-stage renal disease on hemodialysis who presented with persistently elevated serum beta-human chorionic gonadotropin during pretransplant evaluation, despite being sexually inactive. Further evaluation, including a negative urine human chorionic gonadotropin test and imaging studies, confirmed that she was not pregnant. The false-positive result caused significant delays in her eligibility for transplantation, resulting in nearly a month postponement of the procedure.
conclusionFalse-positive beta-human chorionic gonadotropin results are clinically significant in patients with end-stage renal disease and may delay urgent interventions such as kidney transplantation. Clinicians should interpret beta-human chorionic gonadotropin cautiously in this population and consider confirmatory testing-including urine beta-human chorionic gonadotropin assays, imaging, or serum progesterone measurement-before postponing time-sensitive procedures.
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