Evidence mapPaperPMID 42052009Full record

ReviewFrontiers in public health2026

The CIRCULAR model: advancing public health through citizen science initiated clinical and mechanistic research in atrial fibrillation.

Myrthe F Kuipers, Maurice L Remy, Amélie C T Collinet, Kennedy Silva Ramos, Carina A C M Pittens, Michiel van Oudheusden, Ronja Laurila, Jan van der Werke, Elza D van Deel, Umut Konus and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Myrthe F KuipersDepartment of Marketing, Economics and Business Administration, Amsterdam Business School, University of Amsterdam, Amsterdam, Netherlands.
Maurice L RemyAthena Institute, VU Amsterdam, Amsterdam, Netherlands.
Amélie C T CollinetDepartment of Physiology, Amsterdam UMC, Location Vrije Universiteit, Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, Netherlands.
Kennedy Silva RamosDepartment of Physiology, Amsterdam UMC, Location Vrije Universiteit, Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, Netherlands.
Carina A C M PittensAthena Institute, VU Amsterdam, Amsterdam, Netherlands.
Michiel van OudheusdenAthena Institute, VU Amsterdam, Amsterdam, Netherlands.
Ronja LaurilaAtrial Fibrillation Innovation Platform Foundation, Amsterdam, Netherlands.
Jan van der WerkeAtrial Fibrillation Innovation Platform Foundation, Amsterdam, Netherlands.
Elza D van DeelDepartment of Physiology, Amsterdam UMC, Location Vrije Universiteit, Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, Netherlands.
Umut KonusDepartment of Marketing, Economics and Business Administration, Amsterdam Business School, University of Amsterdam, Amsterdam, Netherlands.
Natasja M S de GrootDepartment of Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Bianca J J M BrundelDepartment of Physiology, Amsterdam UMC, Location Vrije Universiteit, Amsterdam Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Citizen science is a transformative approach to advancing health research by bridging the gap between researchers and the public. The Dutch CIRCULAR model, which addresses atrial fibrillation (AF), the most common cardiac arrhythmia worldwide, offers a unique example of applying citizen science in biomedical and public health research. The project was established to systematically include people with AF and their families as partners in research, ensuring that their lived experiences inform priorities, study designs, and interventions. A central role is played by the online health community of the AFIP foundation, which engages the AF community through blog articles, forums, social media, and outreach campaigns. These activities stimulate dialogue, enhance health literacy, empower individuals to contribute hypotheses and solutions, and function as a marketing strategy to attract and retain diverse participants. By sharing outcomes through open-access formats and direct communication with participants, CIRCULAR creates a feedback loop between citizens and researchers that fuels new research directions in AF. Early activities have demonstrated the value of this approach. Patient-reported triggers and suppressors of AF episodes, including psychological stress and lifestyle factors, informed laboratory investigations and led to the co-design of clinical interventions such as dietary programs. These examples illustrate how co-creation can shape both preclinical and clinical research as well as citizen and student education. This review discusses how citizen science is conceptualized and implemented in the CIRCULAR model, presents ongoing and future activities, and reflects on the added value of patient involvement for public health and biomedical innovation. By embedding citizens throughout the research process, and actively engaging them through targeted outreach, CIRCULAR advances patient-centered innovation, strengthens empowerment and health literacy, and provides lessons for future participatory initiatives in complex chronic disease research.

Indexed as

Atrial FibrillationBiomedical ResearchCitizen SciencePublic HealthHumansNetherlandsatrial fibrillationcitizen-scienceco-creationpatient foundationpatient involvement

Identifiers

PMID42052009
PMCPMC13115997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.