ReviewmSphere2026
Small is big: growing impact of small molecule mass spectrometry in infectious disease drug development.
Review in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Small molecule analysis by mass spectrometry (MS) in drug discovery and development has historically focused on confirmation of synthesis products and on drug quantification in pharmacokinetic and pharmacodynamic studies. However, advances in sensitivity, throughput, and cost of mass spectrometers, alongside improvements in data analysis pipelines, have led to increasing contributions of small molecule MS across drug discovery and development stages. In this minireview, I will discuss these recent technical advances in the context of infectious disease drug discovery and development, highlighting applications to high throughput screening and hit identification, the discovery of novel mechanisms of action, personalized treatment and diagnostics, and fighting treatment failure.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.