Evidence map›Paper›PMID 42054088›Full record

ReviewIndian journal of ophthalmology2026

Retinal vein occlusion-related macular edema: An updated review of current evidence and future directions.

Shreyas Temkar, Goutham Rajasekar, Aahan D Shah, Nawazish Shaikh, Amit K Deb, Kalyan Basa

Abstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shreyas TemkarDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Goutham RajasekarDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Aahan D ShahDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Nawazish ShaikhDepartment of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Amit K DebDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Kalyan BasaDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macular edema is the leading cause of visual impairment in retinal vein occlusion (RVO). Management has evolved significantly with advances in retinal imaging and the recognition of vascular endothelial growth factor (VEGF) as a key pathogenic mediator. Anti-VEGF agents are now the mainstay of treatment, supported by robust evidence from randomized clinical trials and real-world studies. Intravitreal corticosteroids play a selective role in patients with suboptimal anti-VEGF responses or contraindications to anti-VEGFs, while the role of laser photocoagulation has become limited. Optical coherence tomography remains central to diagnosis, monitoring, and prognostication. Fluorescein angiography and optical coherence tomography have a role in assessing retinal perfusion, including the macula. Emerging therapies, including biosimilars and long-acting delivery systems, aim to increase accessibility and durability of treatment in RVO-related macular edema (RVO-ME). This review summarizes current evidence and future directions in the management of RVO-ME.

Indexed as

Laser CoagulationMacula LuteaMacular EdemaRetinal Vein OcclusionTomography, Optical CoherenceVisual AcuityAngiogenesis InhibitorsFluorescein AngiographyFundus OculiGlucocorticoidsHumansIntravitreal InjectionsVascular Endothelial Growth Factor AAngiogenesis InhibitorsGlucocorticoidsVascular Endothelial Growth Factor AAnti-VEGFcorticosteroidslaser photocoagulationmacular edemaretinal vein occlusionvitrectomy

Identifiers

PMID42054088
PMCPMC13225321

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.