ArticlePloS one2026
A hybrid CNN-Transformer network integrating multiscale spatially detailed features for medical image segmentation.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
The rapid advancement of deep learning has established Convolutional Neural Networks (CNNs) as mainstream for medical image segmentation, yet their limited receptive field hinders long-range dependency capture. While Transformers excel at modeling global features via self-attention, their high computational complexity burdens high-resolution image processing. To leverage the complementary strengths of both architectures and integrate local and global features under a lightweight framework for enhanced accuracy and efficiency, this work proposes a novel encoder based on parallel CNN and Swin Transformer. Its effective integration is the Semantics and Detail Infusion (SDI) module, which fuses multi-scale features and employs attention to prioritize critical details, enriching features for decoder resolution recovery. Evaluations were conducted on two publicly available datasets, namely the Synapse Multi-Organ Segmentation dataset and the Aortic Vessel Tree dataset. The proposed model achieved Dice coefficients of 84.19% and 87.91%, respectively, and corresponding Hausdorff Distances of 12.64 mm and 7.06 mm. These results represent significant improvements over the UNet benchmark, with Dice score gains of 7.34% and 5.02%, respectively. The results further underscore the model's robustness, efficiency, and clinical relevance in accurately delineating complex anatomical structures, particularly in abdominal segmentation tasks. By effectively fusing CNN and Transformer advantages, our approach meets high-performance standards for medical image segmentation while offering practical benefits for real-world clinical deployment in resource-constrained environments. The code is publicly available on https://github.com/Palpitate-v/HybridNet.
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