Trial reportJournal of cachexia, sarcopenia and muscle2026
Exercise Modalities to Preserve Muscle Mass and Bone Health After Metabolic Bariatric Surgery.
Trial report in Journal of cachexia, sarcopenia and muscle, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04777305 (The POWER BARIATRIC Trial), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The POWER BARIATRIC Trial: Physical Outcomes With Exercise Regimens on BARIATRIC Patients
Who cites it
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Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
backgroundMetabolic bariatric surgery (MBS) effectively reduces fat mass (FM), but how to best preserve muscle and bone mass after MBS is unknown.
objectiveThis study aimed to evaluate the effect of aerobic, resistance and combined exercise regimens on body composition, bone mineral density (BMD) and physical function in adults following MBS.
methodsPatients were randomized into aerobic, resistance, combined and control groups after undergoing MBS. Exercise groups completed a 26-week supervised program (three sessions per week) with progressively increasing intensity. The primary outcome was the change in fat-free mass (FFM) measured by dual-energy X-ray absorptiometry (DXA). Secondary outcomes included FM, hip, femoral neck and lumbar spine BMD, serum collagen type I C-telopeptide (CTX) and physical function (e.g., 6-min walk test and handgrip strength). Between-group differences were assessed using Bayesian analysis of covariance (ANCOVA) adjusted for age, sex, surgery type and baseline body mass index, with credible differences inferred when the 95% credible interval of the standardized effect size excluded zero. Associations between outcomes were assessed using Pearson correlation.
resultsOf 443 eligible candidates, 58 participants (aged 18-65 years, 70% women, BMI 41.7 ± 4.4 kg/m
conclusionsFollowing MBS, combined aerobic and resistance training improved body composition by preserving FFM and reducing FM, while aerobic training most attenuated bone loss. Exercise was associated with modest improvements in physical function, supporting individualized exercise strategies to promote metabolic, musculoskeletal and functional health after MBS. Trial Registration ClinicalTrials.gov Identifier: NCT04777305.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.