ReviewCurrent epidemiology reports2026
Air Pollution Within the Public Health Exposome Framework: Impacts on Cardiovascular Health.
Review in Current epidemiology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose of Review: Ambient air pollution drives cardiovascular disease (CVD), yet single-pollutant models overlook how risk emerges within broader environmental and structural contexts. This review applies the Public Health Exposome (PHE) framework, which integrates natural, built, social, and policy environments, to show how multilevel systems shape CVD vulnerability. Recent Findings: Extreme heat, humidity, and climate variability modify pollutant toxicity, while structural inequities, discriminatory policies, and inadequate planning intensify exposures in marginalized communities. Cumulative psychosocial stress further amplifies inflammatory responses, activating the endo-exposome. Multi-omics studies reveal that pollution alters epigenomic, transcriptomic, and metabolomic pathways linked to inflammation, oxidative stress, and endothelial dysfunction. Emerging tools like machine learning, high-resolution exposure modeling, graph-based analytics, and wearable sensing, enable integration of environmental data and support systems-level approaches. Summary: The PHE framework illustrates how layered environmental and structural stressors accumulate to elevate CVD risk. Reducing this burden requires coupling PHE science with equitable public policy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.