Evidence map›Paper›PMID 42059631›Full record

ArticleMicrobiology spectrum2026

Revisiting cysteine protease function in

Sara De Grandis, Anne Niggli, Delia Bogenstätter, Gaelle Lentini

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara De GrandisInstitute of Cell Biology, University of Bern, Bern, Switzerland.
Anne NiggliInstitute of Cell Biology, University of Bern, Bern, Switzerland.
Delia BogenstätterInstitute of Cell Biology, University of Bern, Bern, Switzerland.
Gaelle LentiniInstitute of Cell Biology, University of Bern, Bern, Switzerland.ORCID 0000-0003-0836-9972

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PZ00P3_209016
6 · The paper itself

Abstract

Chagas disease is a major global health concern affecting millions of people worldwide, with limited therapeutic options in its chronic phase and no prophylactic vaccine. The causative agent, IMPORTANCE: Chagas disease, caused by

Indexed as

Cysteine ProteasesProtozoan ProteinsTrypanosoma cruziAnimalsChagas DiseaseCysteine Proteinase InhibitorsHumansLife Cycle StagesCysteine ProteasesCysteine Proteinase InhibitorsProtozoan ProteinsChagas diseasedifferentiationegresshost-pathogen interactionsneglected tropical diseasesprotease inhibitorsTrypanosoma cruzi

Identifiers

PMID42059631
PMCPMC13228002

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.