ReviewPoultry science2026
Bacillus-based probiotics and fermented products as alternatives to antibiotic growth promoters in poultry: Current perspectives.
Review in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Combined Bifidobacterium bifidum and Bacillus toyonensis supplementation in drinking water improves productive efficiency, physiological status, and meat quality in broiler chickens.Poultry science · 2026Article
- Effects of Dietary Wild Thyme Alone or Combined with Probiotic or Prebiotic Supplementation on Growth Performance, Immune Response, Oxidative Status, and Intestinal Health in Broiler Chickens.Veterinary sciences · 2026Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the years, antibiotic growth promoters (AGPs) have been prophylactically added to the diet of poultry to enhance growth performance and production traits. Mechanisms of AGP action are still poorly understood. Several hypotheses have been proposed to explain the action of AGPs, including reduction in the subclinical intestinal infections, inhibition of toxin releases by intestinal bacteria, and improvement in the absorption of nutrients. However, overuse of AGPs in poultry production may contribute to the emergence of antibiotic resistance. Therefore, many countries have banned the use of AGPs in animal production, driving scientists to explore suitable and effective alternatives to AGPs for commercial use. Probiotics are a sustainable alternative to AGPs, and Bacillus species have been broadly examined for their ability to prevent pathogenic infections and enhance the growth performance of poultry. Currently, liquid-state fermentation is the main strategy used for the production of Bacillus species. However, because of the cost, sustainability, and feasibility concerns associated with this strategy, solid-state fermentation has been attracting increasing attention. In addition to probiotics, Bacillus-based solid-state-fermented products contain Bacillus-derived secondary metabolites with antibacterial activity. Because the main components of Bacillus-based products produced by liquid-state and solid-state fermentation are different, the performance-promoting mechanism of these products will also be different. This review discusses the latest advancements in the application of Bacillus as an alternative to AGPs for promoting gut health and growth performance in poultry. Feasibility assessment of Bacillus-based solid-state-fermented products as AGP alternative and their mechanism of action is also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.