Observational studyBMC women's health2026
Evaluation of endometrium by transvaginal ultrasound and baseline factors as a predictor for endometrial abnormalities in asymptomatic postmenopausal women.
Observational study in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveThe cut-off value of endometrial thickness (ET) in asymptomatic postmenopausal women, beyond which intervention is required, is still debated. This study aimed to provide a clinical decision support tool to guide the management of asymptomatic postmenopausal women with incidentally detected endometrial thickening.
methodsA retrospective observational study was conducted involving 280 asymptomatic postmenopausal women with ET > 5 mm who underwent hysteroscopy or dilation and curettage. Participants were stratified by menopausal duration and history of endocrine therapy for breast cancer. We analysed associations between ET, transvaginal ultrasound (TVUS) features, baseline characteristics and pathological outcomes. Based on univariate and multivariate analyses, we developed a prediction model to help predict endometrial lesions.
resultsThe pathological negativity rate was 35.36% among the whole cohort. We propose two candidate diagnostic thresholds for ET in asymptomatic postmenopausal women: a lower cut-off of 7 mm suggestive of any endometrial pathology (primary outcome), and a higher cut-off of 9.5 mm warranting suspicion for clinically significant pathology, including atypical endometrial hyperplasia (AEH) and endometrial cancer (EC) (secondary outcome). Our findings indicate a statistically significant difference in ET between healthy women within 5 years of menopause and those beyond 5 years. Nevertheless, no such significant disparity was observed in women with endometrial lesions. No significant difference was observed in ET between the overall population and patients receiving postoperative endocrine therapy for breast cancer. Using the presence or absence of endometrial lesions as the outcome, a prediction model was established. The model incorporates age, height, TVUS vessel pattern, and echogenicity. It provides a more holistic risk assessment tool than relying on a single millimetre measurement.
conclusionAdopting a 7 mm candidate cut-off for intervention could spare over one‑third of asymptomatic women from unnecessary invasive procedures. Risk assessment should integrate TVUS morphological features with clinical factors, not merely rely on a single ET measurement. External validation in diverse populations is required before clinical implementation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.