Evidence map›Paper›PMID 42063049›Full record

Trial reportBMC medical education2026

Artificial intelligence-powered virtual standardized patients in teaching history-taking skills to medical students: a randomized controlled trial.

Hai Nguyen Ngoc Dang, Thang Viet Luong, Hoa Thi Ha Vo, Linh Thi Khanh Nguyen, Trung Nguyen Tran, Hong Thi Anh Pham, Huong Thanh Truong, Hoa Tran, Toan Thanh Tran, Tien Anh Hoang and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medical education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hai Nguyen Ngoc Dang *Faculty of Medicine, School of Medicine and Pharmacy, Duy Tan University, Da Nang, Vietnam.
Thang Viet Luong *Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Hoa Thi Ha VoFaculty of Medicine, School of Medicine and Pharmacy, Duy Tan University, Da Nang, Vietnam.
Linh Thi Khanh NguyenFaculty of Medicine, School of Medicine and Pharmacy, Duy Tan University, Da Nang, Vietnam.
Trung Nguyen TranNguyen Tat Thanh Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.
Hong Thi Anh PhamFaculty of Medicine, School of Medicine and Pharmacy, Duy Tan University, Da Nang, Vietnam.
Huong Thanh TruongFaculty of Medicine, Phenikaa University, Ha Noi, Vietnam.
Hoa TranDepartment of Internal Medicine, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. hoa.tran@umc.edu.vn.
Toan Thanh TranVietnam-Cuba Dong Hoi Hospital, Quang Tri, Vietnam.
Tien Anh HoangDepartment of Internal Medicine, University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Thang Chi DoanHue Central Hospital, Hue, Vietnam.
Quan HuynhMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Thomas H MarwickMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) has emerged as a promising tool in medical education. It offers opportunities to enhance learning experiences, particularly through the development of virtual standardized patients (SP) integrated with AI for training purposes. These virtual patients are especially useful for teaching history-taking skills (HTS). However, evidence comparing AI-powered virtual standardized patients (AI-VSP) with traditional SP in teaching HTS remains unclear. This study aimed to evaluate the effectiveness of AI-VSP and compare it with conventional SP in teaching HTS to undergraduate medical students.

methodsA randomized controlled trial (TCTR20251202012) was conducted among third-year medical students at Duy Tan University, Vietnam. This study included participants in the pre-clinical skills curriculum without prior formal HTS training. Students were randomized at the class level to intervention or control groups via a computer-generated sequence. The intervention group practiced with AI-VSP, while the control group learned with conventional SP. Primary outcomes included pre-test, post-test, and objective structured clinical examination (OSCE) scores. Examiners were blinded to group allocation. Student satisfaction was assessed as a secondary outcome using a 5-point Likert scale.

resultsA total of 67 medical students were included, comprising 34 in the AI-VSP group and 33 in the SP group. Both groups demonstrated significant improvement in post-test scores compared with pre-test results (p < 0.001). In the AI-VSP group, the mean score increased from 3.41 ± 2.56 to 8.56 ± 1.85, while in the SP group, it rose from 3.24 ± 1.64 to 7.97 ± 1.85. The magnitude of improvement was 5.15 ± 2.88 in the AI-VSP group and 4.73 ± 1.75 in the SP group (p = 0.503). The mean OSCE scores were 6.5 ± 1.5 for the AI-VSP group and 6.3 ± 1.7 for the SP group (p = 0.543). Mixed-effects modeling adjusting for age and class-level clustering confirmed that neither pre-test, post-test, OSCE scores, nor score improvement differed significantly between instructional methods. Regarding student satisfaction, there was no statistically significant difference in perceived learning experience between the two groups (all p > 0.05).

conclusionsLearning outcomes and student satisfaction did not differ significantly between the AI-VSP and SP instructional methods.

trial registrationTCTR20251202012 (registered on 20/11/2025); retrospectively registered; https://www.thaiclinicaltrials.org/show/TCTR20251202012.

Indexed as

Artificial IntelligenceEducation, Medical, UndergraduateMedical History TakingPatient SimulationStudents, MedicalAdultClinical CompetenceEducational MeasurementFemaleHumansMaleVietnamYoung AdultArtificial intelligenceHistory-taking skillsMedical educationVirtual standardized patient

Identifiers

PMID42063049
PMCPMC13274040

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.