Evidence map›Paper›PMID 42063142›Full record

ArticleNutrition journal2026

Coffee consumption in relation to circadian syndrome in US population: a cross-sectional study.

Da Shi, Jiayi Hang, Weihong Chen, Zhiyu Jiang, Yi He, Jiaqiang Gui, Wei Liu

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In one paragraph

Article in Nutrition journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Da ShiMedical Big Data and Bioinformatics Research Centre, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, 341000, China.
Jiayi HangDepartment of Agricultural, Food and Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, Edmonton, AB, Canada.
Weihong ChenSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, Jiangxi, China.
Zhiyu JiangSchool of Public Health and Health Management, Gannan Medical University, Ganzhou, Jiangxi, China.
Yi HeFirst Clinical College, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Jiaqiang GuiInstitute of Urology, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.
Wei LiuMedical Big Data and Bioinformatics Research Centre, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, 341000, China. liuwe1996@foxmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCircadian syndrome (CircS) was recently proposed and referred to several common chronic diseases that showed a tight association with circadian disruption.

methodsThis study included 15,594 participants from the National Health and Nutrition Examination Survey during 2003-2020. Survey-weight regression was used to examine the relationship between coffee consumption and CircS in the US population. Potential confounders were adjusted in the analysis. Mediation analysis was conducted to explore the mediating role of serum alkaline phosphatase (ALP) in the above relationship.

resultsAfter multivariate adjustment, participants with coffee consumption between one and two cups/day had significant reductions in CircS (OR: 0.976 with 95% CI: 0.960, 0.992) and CircS-related components (β: -0.121 with 95% CI: -0.184, -0.058) compared with those did not consumed coffee. Age, education level, and the ratio of family income to poverty showed interaction with coffee consumption on CircS and/or its components (P

conclusionsOverall, coffee consumption was negatively associated with the risk of CircS and CircS-related components among the US population, and the associations were modified by age, education level, and household income but mediated by decreased serum ALP.

Indexed as

Chronobiology DisordersCircadian RhythmCoffeeAdultAlkaline PhosphataseCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysUnited StatesAlkaline PhosphataseCoffeeAlkaline phosphataseCircadian rhythmsCircadian syndromeCoffee

Identifiers

PMID42063142
PMCPMC13285426

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.