Evidence map›Paper›PMID 42063247›Full record

ArticleDevelopmental neurobiology2026

Vagus Nerve Stimulation Paired With Tones Alters the Auditory Cortex Proteome in a Rat Model of Rett Syndrome.

Isabella K Myers, Fang Bian, Maria P Solano, Yara El Zoghby, Diana Tavares-Ferreira, Tanya Danaphongse, Crystal T Engineer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isabella K MyersDepartment of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.
Fang BianDepartment of Bioengineering, Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas, Richardson, Texas, USA.
Maria P SolanoDepartment of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.
Yara El ZoghbyDepartment of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.
Diana Tavares-FerreiraDepartment of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.
Tanya DanaphongseTexas Biomedical Device Center, The University of Texas at Dallas, Richardson, Texas, USA.
Crystal T EngineerDepartment of Neuroscience, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, USA.

Funding

Autism Research Institute
6 · The paper itself

Abstract

Rett syndrome is a neurodevelopmental disorder caused by an X-linked mutation of the MeCP2 gene. Individuals with Rett syndrome, as well as rodent models of this disorder, demonstrate abnormal cortical responses to sound, which impair auditory discrimination ability. Vagus nerve stimulation (VNS) paired with tones has been shown to drive robust changes in the auditory cortex physiology of Mecp2

Indexed as

Auditory CortexProteomeRett SyndromeVagus Nerve StimulationAcoustic StimulationAnimalsDisease Models, AnimalFemaleMethyl-CpG-Binding Protein 2ProteomicsRatsRats, TransgenicMethyl-CpG-Binding Protein 2Proteomeauditory cortexproteomicsRett syndromeVNS

Identifiers

PMID42063247
PMCPMC13133546

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.