Evidence map›Paper›PMID 42063437›Full record

ArticleFrontiers in pediatrics2026

Identification of risk factors of cystic periventricular leukomalacia in preterm infants.

Renée Lampe, Irina Sidorenko, Eva Lück, Andrey Kovtanyuk, Ursula Felderhoff-Müser, Marcus Krüger, Christian Brickmann

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renée LampeDepartment of Orthopedics and Sport Orthopedics, TUM School of Medicine and Health, Markus Würth Professorship at Technical University of Munich, Technical University of Munich, TUM University Hospital, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Munich, Germany.
Irina SidorenkoDepartment of Orthopedics and Sport Orthopedics, TUM School of Medicine and Health, Markus Würth Professorship at Technical University of Munich, Technical University of Munich, TUM University Hospital, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Munich, Germany.
Eva LückDepartment of Orthopedics and Sport Orthopedics, TUM School of Medicine and Health, Markus Würth Professorship at Technical University of Munich, Technical University of Munich, TUM University Hospital, Research Unit for Paediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Munich, Germany.
Andrey KovtanyukDepartment of Mathematics, Technical University of Munich, TUM School of Computation, Information and Technology (CIT), Munich, Germany.
Ursula Felderhoff-MüserDepartment of Paediatrics I, Neonatology, Paediatric Intensive Care, Paediatric Infectious Diseases, Paediatric Neurology, Centre for Translational Neuro- and Behavioural Sciences, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.
Marcus KrügerClinic for Neonatology, Munich Clinic Harlaching & Schwabing, Munich, Germany.
Christian BrickmannClinic for Neonatology, Munich Clinic Harlaching & Schwabing, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The neonatal period in very preterm born infants is characterized by high vulnerability of the developing brain. Diffuse or cystic white matter injury-cystic periventricular leukomalacia (cPVL)-is one of the most serious complications leading to brain injury in preterm infants, associated with an increased risk of neurological impairments such as cerebral palsy. Methods: In the present study, parameters that may potentially influence the occurrence of cPVL are analyzed. The study is based on retrospective clinical data of 46 preterm infants with and without cPVL, including prenatal factors, birth-related information, neonatal diagnoses and routinely measured clinical monitoring data. The novelty of this work lies in the inclusion in analyses of cerebral blood flow (CBF), CBF fluctuations and partial pressure of oxygen in brain tissue (PtO Results: Statistical analyses revealed significant association between cPVL and a group of 5 clinical and 23 regularly measured parameters including mathematically calculated CBF, CBF fluctuations and PtO

Indexed as

cerebralblood flowcerebral tissue oxygenationextremely and very preterm infantshypoxiapartial pressure of oxygen in brain tissueperiventricular leukomalaciarisk factorswhite matter injury

Identifiers

PMID42063437
PMCPMC13124991

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.