Evidence mapPaperPMID 42063524Full record

ArticleRSC advances2026

Design, synthesis, enzymatic and

Shereen, Ayesha Tahir, Awais Ahmed, Muhammad Saeed Jan, Nouman Aslam, Sohail Hassan, Umer Rashid

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

ShereenDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi Karachi-75270 Pakistan shassan@uok.edu.pk.
Ayesha TahirDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus 22060 Abbottabad Pakistan umerrashid@cuiatd.edu.pk.
Awais AhmedDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus 22060 Abbottabad Pakistan umerrashid@cuiatd.edu.pk.
Muhammad Saeed JanDepartment of Pharmacy, University of Swabi Anbar 23430 Khyber Pakhtunkhwa Pakistan.ORCID https://orcid.org/0000-0003-2411-6510
Nouman AslamDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus 22060 Abbottabad Pakistan umerrashid@cuiatd.edu.pk.
Sohail HassanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi Karachi-75270 Pakistan shassan@uok.edu.pk.
Umer RashidDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus 22060 Abbottabad Pakistan umerrashid@cuiatd.edu.pk.ORCID https://orcid.org/0000-0002-2419-3172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multifactorial and complex pathophysiology of type 2 diabetes mellitus (T2DM) requires therapeutic interventions that regulate key enzymes involved in glucose homeostasis. The study described the design of a new family of oxadiazole-tetrahydropyrimidinone hybrid compounds (18-23 and 30-36), their synthesis, and the testing of these compounds as multitarget antidiabetic agents. The

Identifiers

PMID42063524
PMCPMC13125983

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.