Photoactivated Signaling Networks using DNA-Based Synthetic Organelles as Biomimetic Protocells.

Huiying Xue, Yunlong Qin, Yichen Han, Shijun Xu, Itamar Willner, Fan Xia, Fujian Huang

Abstract read

In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huiying XueState Key Laboratory of Geomicrobiology and Environmental Changes, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, China.

Yunlong QinThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.

Yichen HanThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.

Shijun XuState Key Laboratory of Geomicrobiology and Environmental Changes, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, China.

Itamar WillnerThe Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0001-9710-9077

Fan XiaState Key Laboratory of Geomicrobiology and Environmental Changes, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, China.ORCID 0000-0001-7705-4638

Fujian HuangState Key Laboratory of Geomicrobiology and Environmental Changes, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, China.ORCID 0000-0002-7777-1589

Funding

National Key R&D Program of China 2021YFA1200403National Natural Science Foundation of China 22090050National Natural Science Foundation of China 22377112National Natural Science Foundation of China U24A20502Natural Science Foundation of Shenzhen JCYJ20220530162406014

6 · The paper itself

Abstract

Membraneless organelles formed by phase-separated nucleic acid or protein condensates play vital roles in regulating cellular functions. Integrating such synthetic organelles into protocell carriers remains a key challenge. Here, we introduce a method to assemble functional phase-separated organelles within liposome protocells. Pre-engineered nucleic acids are encapsulated with ligase in locked-DNA-nanopore modified protocells. Upon nanopore unlocking and Mg

Indexed as

Artificial CellsBiomimetic MaterialsBiomimeticsDNAOrganellesDNA, CatalyticDNA NanostructuresLiposomesPhotochemical ProcessesSignal TransductionDNADNA, CatalyticLiposomesDNA condensateDNAzymeliposomephotoresponsivetranscription

Identifiers

PMID42065640

DOI10.1002/anie.4889049

PMCPMC13266963

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.