Evidence map›Paper›PMID 42068258›Full record

ArticleJournal of the American Geriatrics Society2026

Association Between ICD-Coded Delirium and Health Determinants in The Atherosclerosis Risk in Communities Study.

Mfon E Umoh, Emmanuel E Garcia Morales, Wuyang Zhang, Charles H Brown, Esther S Oh, Nicholas S Reed

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mfon E UmohDepartment of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Emmanuel E Garcia MoralesDepartment of Population Health, Optimal Aging Institute, NYU Grossman School of Medicine, New York, New York, USA.
Wuyang ZhangDepartment of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0009-0007-8726-6520
Charles H BrownDepartment of Anesthesiology, Stanford University, California, USA.
Esther S OhDepartment of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nicholas S ReedDepartment of Population Health, Optimal Aging Institute, NYU Grossman School of Medicine, New York, New York, USA.

Funding

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - COORDINATING CENTER - TASK AREA B.2 AND B.375N92022D00001 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID · 2022 to 2025
$13.7M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2 of 5U01HL096917 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI MOSLEY, THOMAS H · 2010 to 2018
$11.9M
ARIC Neurocognitive Study (ARIC-NCS) Renewal UNC 4 of 5U01HL096899 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID J · 2010 to 2018
$7.5M
ARIC Neurocognitive Study (ARIC-NCS)U01HL096902 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2010 to 2018
$7.4M
Remote Data Enclave Core (RDEC)P30AG066587 · NIA · JOHNS HOPKINS UNIVERSITY · PI Kali St. Marie Thomas · 2020 to 2026
$6.7M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 4 of 5U01HL096814 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUGHES, TIMOTHY M., WAGENKNECHT, LYNNE E · 2010 to 2018
$6.5M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00003 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2022 to 2025
$5.1M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WAGENKNECHT, LYNNE · 2022 to 2025
$5.0M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00004 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI WINDHAM, BEVERLY GWEN · 2022 to 2025
$4.8M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00002 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF · 2022 to 2025
$4.7M
Health Services and Outcomes Research for Aging PopulationsT32AG066576 · NIA · JOHNS HOPKINS UNIVERSITY · PI CYNTHIA Melinda BOYD, Jennifer L. Wolff · 2020 to 2026
$3.8M
NCATS NIH HHS K12 TR004925NCATS NIH HHS K12TR004925NHLBI NIH HHS 75N92022D00001NHLBI NIH HHS 75N92022D00002NHLBI NIH HHS 75N92022D00003NHLBI NIH HHS 75N92022D00004NHLBI NIH HHS 75N92022D00005NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NIA NIH HHS K23 AG065443NIA NIH HHS K23AG065443NIA NIH HHS L30 AG089733NIA NIH HHS P30 AG066587NIA NIH HHS P30AG066587NIA NIH HHS T32 AG066576NIA NIH HHS T32AG066576
6 · The paper itself

Abstract

importanceDelirium is common among hospitalized adults, prevalence estimates ranging from 33% to 50% of hospitalized patients over age 65. Yet, little is known about the association between social determinants of health (SDOH) and delirium.

objectiveTo describe neighborhood-level risk factors for hospitalization with delirium. We examined the association between hospitalization with delirium and neighborhood disadvantage, measured by the Area Deprivation Index (ADI)-a tool that measures SDOH by assessing socioeconomic conditions and disadvantages within a geographic area.

methodsThe Atherosclerosis Risk in Communities (ARIC) study is a community-based prospective cohort of adults recruited from four US communities. This analysis included ARIC participants that attended visit 5 (2011-2013) and had at least one hospitalization before visit 7 (2018-2019). Delirium was identified and quantified using hospital claim records. The association between ADI quartiles and incidence and number of delirium events was estimated with offset Poisson regression models for the time participants were observed. Associations were also examined by cognitive status.

resultsIn this analytic cohort of 4130 participants, 486 (11.8%) experienced at least one hospitalization with delirium. Unadjusted regression analyses showed a higher incidence of delirium (proportion ratio, PR = 1.32; and 95% CI = 1.03, 1.69) and number of delirium events (incidence rate ratio, IRR = 1.30; 95% CI = 1.05, 1.63) among participants from the highest ADI quartile compared to the lowest quartile. In fully adjusted models, this association was attenuated. Among participants with mild cognitive impairment (MCI) and dementia, those from the most disadvantaged neighborhoods experienced a higher incidence and number of delirium events.

conclusionIn this cohort of hospitalized older adults, participants from more disadvantaged neighborhoods had a higher incidence of delirium; this association was attenuated in adjusted analyses. This suggests that neighborhood-level social disadvantage may be meaningful in studies on prevention and management of delirium, though overlapping demographic and clinical characteristics likely confound this relationship.

Indexed as

AtherosclerosisDeliriumHospitalizationSocial Determinants of HealthAgedFemaleHumansIncidenceMaleNeighborhood CharacteristicsProspective StudiesResidence CharacteristicsRisk FactorsSocioeconomic Disparities in HealthUnited Statesdeliriumdementiahospitalizationsocial determinants of health

Identifiers

PMID42068258
PMCPMC13254706

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.