Evidence map›Paper›PMID 42072202›Full record

ReviewBioengineering (Basel, Switzerland)2026

Anionic Polysaccharides: Promising 3D Bioink Candidates for Tissue Engineering.

Feiyang Wang, Redouan El Boutachfaiti, Gustavo Cabrera-Barjas, Cédric Delattre

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Feiyang WangUniversité Clermont Auvergne, Clermont Auvergne INP, Institut Pascal, Centre National De La Recherche Scientifique (CNRS), 63000 Clermont-Ferrand, France.
Redouan El BoutachfaitiUMRT INRAE 1158 BioEcoAgro, BIOlogie des Plantes et Innovation (BIOPI), Avenue des Facultés, IUT d'Amiens, Université de Picardie Jules Verne, Le Bailly, 80025 Amiens, France.ORCID 0000-0002-5772-8030
Gustavo Cabrera-BarjasFacultad de Ciencias de la Rehabilitación y Calidad de Vida, Escuela de Nutrición y Dietética, Universidad San Sebastián Campus Las Tres Pascualas, Lientur 1439, Concepción 4080871, Chile.ORCID 0000-0002-1850-0244
Cédric DelattreUniversité Clermont Auvergne, Clermont Auvergne INP, Institut Pascal, Centre National De La Recherche Scientifique (CNRS), 63000 Clermont-Ferrand, France.ORCID 0000-0003-3605-1929

Funding

China Scholarship Council 202208330024
6 · The paper itself

Abstract

Anionic polysaccharides are sugars with a negative charge. Common examples include alginic acid, hyaluronic acid, pectin, chondroitin sulfate, and heparin. These molecules are bioactive and widely used in medicine, food, and cosmetics. On their own, they usually do not bind to cells. However, they can serve as bioinks or as parts of bioink mixtures. In 3D bioprinting, anionic polysaccharides are often combined with natural polymers like collagen or with synthetic materials to form hydrogels. These hydrogels act as scaffolds that give cells a three-dimensional space to grow and form tissue. The properties of these hydrogels can be tuned to match specific needs. Together, anionic polysaccharides and 3D bioprinting offer strong potential for tissue engineering, making it possible to build complex, custom tissue structures that may help solve problems in organ repair and replacement. This review summarizes the sources, structures, and key properties of Common anionic polysaccharides, with a comparative analysis of their chemical, biological, and mechanical characteristics and recent 3D printing strategies. It highlights the advantages of anionic polysaccharide bioinks, particularly their compatibility with enzymatic, photo-, and ionic crosslinking, and presents representative examples demonstrating their suitability for diverse tissue engineering applications and printing requirements.

Indexed as

3D bioprintinganionic polysaccharidesynthetic polysaccharidetissue engineering

Identifiers

PMID42072202
PMCPMC13113944

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.