ArticleBiomolecules2026
Combining IR and Raman Spectroscopies for Enhanced Accuracy and Precision in the Determination of Lipid Composition in Liposomes.
Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Reducing measurement uncertainty is crucial to enable the adoption of rapid point-of-use techniques for clinical and industrial applications. Diagnosis of neonatal respiratory distress syndrome and liposome formulation quality control are two applications for which measuring the ratio of the lecithin to sphingomyelin composition of liposomes is important, for which no rapid measurement currently exists. Raman and infrared spectroscopies are two complementary approaches to examine characteristic molecular vibrations that can spectroscopically measure liposomes and, when combined with machine learning, predict their composition. We show that employing a data-fusion approach the uncertainty in the predicted compositions compared to the individual modalities (IR
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