Evidence mapPaperPMID 42072736Full record

ArticleBiomolecules2026

Resilience to Diabetic Retinopathy (RDR) Is Associated with a Pre-Retinopathy Transcriptional Program Induced by Diabetes.

Janani Rajasekar, Maria Paula Zappia, Maximilian A McCann, Maxim V Frolov, Andrius Kazlauskas

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janani RajasekarDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL 60612, USA.
Maria Paula ZappiaDepartment of Biochemistry and Molecular Genetics, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-0449-5445
Maximilian A McCannDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-8661-430X
Maxim V FrolovDepartment of Biochemistry and Molecular Genetics, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-3953-3739
Andrius KazlauskasDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-1919-3327

Funding

Illinois Society for the Prevention of Blindness NANIH HHS 2P30EY001792-15NIH HHS 2R01EY031350-05Research to Prevent Blindness NARetina Research Foundation NA
6 · The paper itself

Abstract

The purpose of this project was to define gene expression changes associated with the acquisition and loss of resilience to diabetic retinopathy (RDR) in individual retinal cell types. A non-immune form of type 1 diabetes mellitus (DM) was induced by injecting male

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Diabetic RetinopathyTranscription, GeneticAnimalsEpendymoglial CellsGene Expression RegulationMaleMiceMice, Inbred C57BLRetinadiabetic retinopathyMüller cellsresilience to diabetic retinopathysingle-cell RNA sequencing

Identifiers

PMID42072736
PMCPMC13114160

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.