Evidence mapPaperPMID 42073274Full record

ArticleFoods (Basel, Switzerland)2026

The Hidden Metabolites in Glutinous Rice Huangjiu and Their Antioxidant Potential.

Qingxia Zhao, Jingyi Song, Xukai Li, Zhongwei Zhang, Junsong Xiao, Hua Wu, Mingquan Huang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qingxia ZhaoDepartment of Food Science and Engineering, School of Food and Health, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.
Jingyi SongDepartment of Food Science and Engineering, School of Food and Health, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.
Xukai LiMiscellaneous Grain Molecular Breeding Team, College of Agriculture, Shanxi Agricultural University, Taigu 030801, China.ORCID 0000-0001-7248-1331
Zhongwei ZhangDepartment of Light Chemical Engineering, School of Light Industry Science and Engineering, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.
Junsong XiaoSchool of Food and Health, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.ORCID 0000-0001-6778-8187
Hua WuSchool of Light Industry Science and Engineering, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.ORCID 0000-0002-6916-1596
Mingquan HuangSchool of Food and Health, Beijing Technology and Business University, Higher Education Garden, Liangxiang, Fangshan District, Beijing 102488, China.

Funding

Beijing Municipal Education Commission KM202010011010Shanxi Houji Laboratory 2025HJY01
6 · The paper itself

Abstract

Glutinous rice huangjiu, a non-distilled wine variety unique to China, is rich in nutrients. However, systematic research on the differences in its non-volatile functional components remains scarce, despite these variations being key factors influencing its antioxidant effects. This study employed non-targeted metabolomics to systematically analyze the non-volatile metabolite profiles of 16 glutinous rice huangjiu brands, identifying 1450 metabolites. An alcohol-induced hepatocyte injury model was established, combining cell viability and reactive oxygen species (ROS) level assays to screen for samples (G10 and G11) exhibiting significant efficacy across varying alcohol concentrations. Differential metabolite analysis further identified key bioactive compounds including L-proline, dihydroferulic acid, chalcones, and multiple phenolic derivatives. Using molecular docking technology, we preliminarily revealed that these components may exert antioxidant and hepatoprotective effects either by directly scavenging free radicals or indirectly through mechanisms such as participating in glutathione metabolism and regulating the KEAP1-Nrf2 signaling pathway. This study elucidates the differences among glutinous rice huangjiu at the metabolomic and cellular model levels, providing a scientific basis for evaluating the health benefits and developing new products of huangjiu.

Indexed as

alcoholic liver injuryantioxidantglutinous rice huangjiunon-targeted metabolomics

Identifiers

PMID42073274
PMCPMC13115478

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.