Evidence map›Paper›PMID 42073565›Full record

ReviewCancers2026

The Intraoperative Golden Hour in Minimally Invasive Parafascicular Surgery for Brain Tumors.

José Pedro Lavrador, Yasir A Chowdhury, Filippo Andrea Sinosi, Francesco Marchi, Vindhya Prasad, Oktay Genel, Ana Mirallave-Pescador, Alba Diaz-Baamonde, Richard Gullan, Keyoumars Ashkan and 2 more

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

José Pedro LavradorDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0002-9518-111X
Yasir A ChowdhuryDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Filippo Andrea SinosiDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0001-8869-8631
Francesco MarchiDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0001-6532-7168
Vindhya PrasadDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0003-3852-3096
Oktay GenelDepartment of Neurosurgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Ana Mirallave-PescadorDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Alba Diaz-BaamondeDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0002-1256-516X
Richard GullanDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Keyoumars AshkanDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Francesco VerganiDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Ranjeev BhangooDepartment of Neurosurgery, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimally invasive parafascicular surgery (MIPS) represents a paradigm shift in the management of deep-seated brain tumors, enabling function-sparing resections previously limited to biopsy and/or medical therapy. Central to MIPS are structured frameworks guiding preoperative planning and intraoperative execution. The six-pillar concept-comprising imaging, navigation, atraumatic access, optics, resection, and postoperative care-provides a comprehensive approach to integrate advanced neuroimaging, tractography, tubular retractor systems, fluorescence-guided resection, and neuromonitoring to optimize functional outcomes. Five-point target-trajectory complex planning-craniotomy, outer radial corridor, inner radial corridor, target, and resection margins-translates preoperative imaging and functional mapping into a precise surgical trajectory, balancing maximal tumor resection with minimal disruption of eloquent brain structures. Preoperative assessment of tumor characteristics, vascular relationships, and cortical eloquence informs trajectory planning and intraoperative adjustments. A critical determinant of MIPS success is the

Indexed as

craniotomygolden hourminimally invasive parafascicular approachneuromonitoringneuro-oncologytractographytubular retractor

Identifiers

PMID42073565
PMCPMC13115230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.