Evidence mapPaperPMID 42074136Full record

ArticleInternational journal of molecular sciences2026

Synthesis and Characterization of a Novel Biphenol-Based Gadolinium Complex for Encapsulation in Human Red Blood Cells.

Antonella Antonelli, Riccardo Di Corato, Luca Mancini, Michela Cangiotti, Laura Valentini, Luca Giorgi, Gianluca Ambrosi, Pietro Gobbi, Erika Palazzetti, Luigia Rossi and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonella AntonelliDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0002-5931-4616
Riccardo Di CoratoInstitute for Microelectronics and Microsystems (IMM), CNR, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-7173-6176
Luca ManciniDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0002-3479-7324
Michela CangiottiDipartimento di Scienze Pure e Applicate (DiSPeA), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0002-5713-7740
Laura ValentiniDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0001-8028-1233
Luca GiorgiDipartimento di Scienze Pure e Applicate (DiSPeA), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.
Gianluca AmbrosiDipartimento di Scienze Pure e Applicate (DiSPeA), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0003-1046-0871
Pietro GobbiDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0003-4705-0833
Erika PalazzettiDipartimento di Scienze Pure e Applicate (DiSPeA), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0002-3376-562X
Luigia RossiDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.
Mauro MagnaniDipartimento di Scienze Biomolecolari (DISB), Università degli Studi di Urbino Carlo Bo, Campus Scientifico "E. Mattei", Via Cà Le Suore 2-4, 61029 Urbino, Italy.ORCID 0000-0001-6456-6626

Funding

European Union—NextGenerationEU, Mission 4, Component 2, under the Italian Ministry of University and Research (MUR) ECS_00000041
6 · The paper itself

Abstract

Gadolinium-based contrast agents are widely used in clinical magnetic resonance imaging (MRI) due to their strong paramagnetic properties and ability to enhance image contrast. Despite their diagnostic value, concerns remain regarding gadolinium toxicity and long-term tissue retention, particularly for less stable linear chelates. In this study, we report preliminary results on a newly synthesized gadolinium-based compound (L-Gd), in which the Gd

Indexed as

Contrast MediaErythrocytesGadoliniumHemolysisHumansMagnetic Resonance ImagingContrast MediaGadoliniumbiocompatibilityGd complex synthesisGd-loaded RBCsmethodologiesred blood cells (RBCs)

Identifiers

PMID42074136
PMCPMC13116415

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.