Evidence map›Paper›PMID 42074628›Full record

ReviewJournal of clinical medicine2026

Exercise-Based Cardiac Rehabilitation for Peripheral Artery Disease.

Francesco Giallauria, Mario Pacileo, Gianluigi Cuomo, Giuseppe Vallefuoco, Fabrizio Catalini, Crescenzo Testa, Cristina Savarese, Alfredo Mauriello, Carmine Izzo, Michele Ciccarelli and 2 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesco GiallauriaDepartment of Translational Medical Sciences, Federico II University of Naples, via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-4119-9397
Mario PacileoCardiology and Intensive Care Unit, Department of Cardiology, "Umberto I" Hospital, 84014 Nocera Inferiore, Italy.ORCID 0000-0002-6330-1738
Gianluigi CuomoDepartment of General Medicine, "Ospedale del Mare", ASL Napoli 1 Centro, 80147 Naples, Italy.ORCID 0009-0008-1756-9638
Giuseppe VallefuocoCardiology Unit, "V. Monaldi" Hospital, University of Campania "Luigi Vanvitelli", 80131 Naples, Italy.
Fabrizio CataliniDepartment of Translational Medical Sciences, Federico II University of Naples, via S. Pansini 5, 80131 Naples, Italy.
Crescenzo TestaDepartment of Translational Medical Sciences, Federico II University of Naples, via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-8360-5173
Cristina SavareseCardiology and Intensive Care Unit, Department of Cardiology, "Umberto I" Hospital, 84014 Nocera Inferiore, Italy.
Alfredo MaurielloCardiology Unit, Institute National Cancer, IRCCS, Foundation "G. Pascale", 80131 Naples, Italy.ORCID 0000-0001-7060-6938
Carmine IzzoDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84084 Salerno, Italy.ORCID 0000-0001-8499-5428
Michele CiccarelliDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84084 Salerno, Italy.ORCID 0000-0003-2379-1960
Vincenzo RussoCardiology Unit, Department of Medical and Translational Sciences, University of Campania "Luigi Vanvitelli", "V. Monaldi" Hospital, University of Campania "L. Vanvitelli", 80131 Naples, Italy.ORCID 0000-0002-9227-0360
Antonello D'AndreaCardiology and Intensive Care Unit, Department of Cardiology, "Umberto I" Hospital, 84014 Nocera Inferiore, Italy.ORCID 0000-0002-9698-9145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral artery disease (PAD) is a pervasive atherosclerotic condition affecting well over 100 million adults worldwide and associated with major functional limitations, reduced quality of life, and elevated risks of myocardial infarction, stroke, limb events, and mortality. Exercise therapy-preferably supervised or delivered through structured, monitored home-based programs-is a first-line, guideline-endorsed therapy that improves walking performance and patient-reported outcomes and contributes to comprehensive secondary prevention. This review synthesizes mechanistic underpinnings (endothelial, angiogenic, metabolic, and autonomic) and appraises the comparative effectiveness, safety, and implementation models of supervised exercise therapy (SET), structured home-based and hybrid programs, and alternative modalities in PAD. Finally, we summarize policy aspects and persistent gaps to guide clinical practice and future research.

Indexed as

cardiac rehabilitationexercise trainingperipheral artery disease

Identifiers

PMID42074628
PMCPMC13115731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.