Evidence map›Paper›PMID 42075521›Full record

SynthesisMedicina (Kaunas, Lithuania)2026

Efficacy and Safety of Vagus Nerve Stimulation for Hospitalized COVID-19 Patients: A Systematic Review and Methodological Evaluation of Randomized Controlled Trials.

Adrian Balan, Giles Graham, Herban Sorin, Marius Marcu, Nini Gheorghe, Mara Gabriela, Andreea-Roxana Florescu, Alina-Mirela Popa, Ana Lascu, Cristian Ion Mot and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Adrian BalanCenter for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0009-0005-0519-5868
Giles GrahamEurope to Europe, 78 Providence Park, Southampton SO16 7QW, UK.
Herban SorinDepartment of Civil Engineering and Installations, Polytechnic University of Timisoara, 300006 Timisoara, Romania.
Marius MarcuDepartment of Computer and Software Engineering, Polytechnic University of Timisoara, 300006 Timisoara, Romania.ORCID 0000-0003-3394-385X
Nini GheorgheFaculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Mara GabrielaFaculty of Medicine, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Andreea-Roxana FlorescuCenter for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Alina-Mirela PopaCenter for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0009-0005-6026-8724
Ana LascuDepartment of Functional Sciences, Discipline of Pathophysiology, Centre for Translational Research and Systems Medicine, University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.ORCID 0000-0003-0600-1103
Cristian Ion MotOtorhinolaryngology Department, Municipal Emergency Hospital Timisoara, 300041 Timisoara, Romania.
Stefan MihaicutaCenter for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0001-8897-8342
Stefan Marian FrentCenter for Research and Innovation in Precision Medicine of Respiratory Diseases, Department of Pulmonology, University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0002-7469-6755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Vagus Nerve StimulationHospitalizationHumansRandomized Controlled Trials as TopicTreatment OutcomeAI toolscholinergic anti-inflammatory pathwayCOVID-19cytokine stormneuromodulationrandomized controlled trialsrisk of biasSARS-CoV-2systematic reviewvagus nerve stimulation

Identifiers

PMID42075521
PMCPMC13117116

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.