Evidence map›Paper›PMID 42075804›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Mechanism of Astragaloside IV Against Cerebral Ischemia-Reperfusion Injury: Inhibiting Neuronal Apoptosis via the CytC/Apaf-1 Mitochondrial Pathway.

Tongtong He, Zhe Zhang, Xiaohong Zhou, Ping Gao, Zhenyi Liu, Yanmeng Zhao, Hua Liang, Weijuan Gao, Xiaofei Jin

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tongtong HeHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Zhe ZhangTraditional Chinese Medicine Program, Graduate School, Juquan Campus, Hebei University of Chinese Medicine, No. 326, Xinshinan Road, Qiaoxi District, Shijiazhuang 050091, China.
Xiaohong ZhouHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Ping GaoHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Zhenyi LiuHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Yanmeng ZhaoHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Hua LiangHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Weijuan GaoHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.
Xiaofei JinHebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Hebei University of Chinese Medicine, No. 3 Xingyuan Road, Luquan District, Shijiazhuang 050200, China.

Funding

Hebei Province Natural Science Foundation Project No. H2022423382Hebei Provincial Administration of Traditional Chinese Medicine Scientific Research Program No.2021101Joint Key Project of Traditional Chinese Medicine, Hebei Provincial Natural Science Foundation No.H2025423053National Natural Science Foundation of China No.81873180pecial Project of Basic Scientific Research Business Funds of Provincial Universities of Hebei University of Chinese Medicine No.TDZR2024010Yanzhao Medical Research Project, Hebei University of Chinese Medicine No.YZZQ2022002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

astragaloside IVcerebral ischemic reperfusion injuryCytC/Apaf-1 pathwaymolecular dynamics simulationneuron apoptosis

Identifiers

PMID42075804
PMCPMC13119190

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.