Observational studyWomen's health (London, England)
Post-stroke cognitive decline among women in midlife.
Observational study in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is a significant risk factor for cognitive impairment. Women face a heightened risk due to their longer life expectancy and the greater prevalence of stroke-related disability.
objectiveTo compare the trajectory of cognitive decline in women with and without a stroke diagnosis and assessed demographic differences.
designThe study employed a longitudinal, observational cohort design.
methodsThe Study of Women's Health Across the Nation interviewed women in their 40s and 50s from seven U.S. cities approximately yearly to collect information on their physical, biological, psychological, and social health. Cognitive assessments were conducted between 2000 (Wave 4) and 2008 (Wave 10) that were designed to examine information processing speed, working memory, immediate memory, and delayed memory. Adjusting for baseline age, race/ethnicity, income, education, marital status, comorbidities, and insurance, generalized linear mixed models were used to compare cognitive decline between women who had experienced a stroke and those who had not.
resultsAmong the 3302 women in the sample, age was 49.52 (SD = 2.64) years old at baseline and 53.74 (SD = 3.94) in the final wave. In Wave 4, only 0.67% (
conclusionThese findings underscore the persistent impact of stroke on multiple cognitive domains in midlife women, with a more significant decline observed among Black women. Targeted prevention and rehabilitation efforts are needed to address both the cognitive consequences of stroke and the demographic differences in post-stroke outcomes.
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