Evidence map›Paper›PMID 42076988›Full record

ArticleClinical endoscopy2026

Echoendoscopic evaluation of the vascular pattern of solid pancreatic lesions as a predictor of neuroendocrine neoplasms: a retrospective study in Mexico.

Edgardo Amaya-Fragoso, José Guillermo de la Mora-Levy, Uriel Isaías Martín-Flores

Abstract read
In one paragraph

Article in Clinical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Edgardo Amaya-FragosoGastrointestinal Endoscopy Department, Instituto Nacional de Cancerología, Mexico City, Mexico.
José Guillermo de la Mora-LevyGastrointestinal Endoscopy Department, Instituto Nacional de Cancerología, Mexico City, Mexico.
Uriel Isaías Martín-FloresGastrointestinal Endoscopy Department, Instituto Nacional de Cancerología, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic ultrasonography (EUS) is essential for evaluating solid pancreatic lesions (SPL). Pancreatic neuroendocrine neoplasms (pNEN) account for 2% of SPL and typically show hypervascularity. This study aimed to assess whether a specific vascular pattern could predict pNEN.

methodsPatients who underwent EUS for a SPL and were histologically diagnosed with pNEN were included. Tissues were obtained using endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) and/or surgical resection. Power Doppler was used to assess the vascular patterns. Patients with pNEN were compared to those diagnosed with pancreatic ductal adenocarcinoma during the same period. Group comparisons by size and histological grade were performed using the chi-square test. Logistic regression analysis identified the EUS features associated with pNEN.

resultsAmong 125 patients (43 pNEN), a peripheral vascular rim (PVR) was associated with pNEN (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.7-8.5; p=0.03), with 100% specificity. Hypervascularity (OR, 3.8; 95% CI, 1.1-13.4; p=0.03) and pancreatic atrophy (OR, 0.3; 95% CI, 0.1-0.9; p=0.04) were also associated.

conclusionsPVR demonstrated 100% specificity and 34.9% sensitivity for pNEN diagnosis, serving as a rule-in sign. PVR visualization may aid in differential diagnosis when EUS-FNB is unavailable or inconclusive.

Indexed as

EndoscopyNeuroendocrine tumorsPancreatic neoplasms

Identifiers

PMID42076988
PMCPMC13254647

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.