Evidence map›Paper›PMID 42076993›Full record

SynthesisExpert reviews in molecular medicine2026

The Effect of Acupuncture in Women with Polycystic Ovary Syndrome Undergoing in vitro Fertilization: A Systematic Review and Meta-Analysis.

Lina Yi, Haolin Zhang, Tian Tian, Yaodong Zhang, Yanru Lou, Jialin Li, Chenhong Liu, Caihong Ma, Ping Liu, Rong Li and 3 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Expert reviews in molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lina YiState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Haolin ZhangState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Tian TianState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Yaodong ZhangState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.ORCID 0009-0001-6384-5372
Yanru LouState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Jialin LiState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.ORCID 0000-0003-3682-1495
Chenhong LiuState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Caihong MaState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Ping LiuState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Rong LiState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.ORCID 0000-0003-0305-5579
Jie QiaoState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Shuo HuangState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Rui YangState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.ORCID 0000-0002-6381-5202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcupuncture is increasingly used during in vitro fertilization and embryo transfer (IVF-ET), but its therapeutic benefits for women with polycystic ovary syndrome (PCOS) remain uncertain.

methodsEight databases were investigated from the inception until April 1, 2024. We screened randomized controlled trials (RCTs) using acupuncture undergoing IVF-ET, the population was patients with PCOS.

resultsWe analyzed 13 RCTs with 1,203 patients. Acupuncture significantly improved clinical pregnancy rate (P < 0.01), high-quality embryo rate (P < 0.01), and live birth rate (P < 0.01). It also reduced gonadotropin (Gn) dose (P = 0.0002), Gn duration (P = 0.005), and OHSS incidence (P < 0.01). No significant differences were seen in fertilization rate, oocyte yield, endometrial thickness, progesterone, LH, E2, miscarriage rate, or cycle cancellation rate.

conclusionsOur results showed that acupuncture therapy could increase the high-quality embryo rate, live birth rate and also the clinical pregnancy rate in PCOS patients undergoing IVF. Acupuncture could reduce the dose and duration of Gn. It also decreased the incidence of OHSS. Based on the result of this meta-analysis, acupuncture therapy is suggested in the IVF process for PCOS patients.

Indexed as

Acupuncture TherapyFertilization in VitroInfertility, FemalePolycystic Ovary SyndromeEmbryo TransferFemaleHumansLive BirthPregnancyPregnancy RateRandomized Controlled Trials as TopicTreatment OutcomeacupunctureinfertilityIVF-ETmeta-analysisPCOS

Identifiers

PMID42076993
PMCPMC13255536

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.