ArticleGlobal implementation research and applications2026
Disseminating a Pediatric Oncology Critical Care Intervention in Latin America and Spain: An Integrated-Knowledge-Translation Approach.
Article in Global implementation research and applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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39 authors.
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Abstract
PROACTIVE (Pediatric Oncology Capacity Assessment Tool for Intensive Care) is a quality improvement (QI) intervention that assist pediatric onco-critical care teams identify institutional strengths and gaps, but language barriers have limited its global uptake. This study aimed to evaluate the translation, refinement, and dissemination of Spanish-PROACTIVE guided by an integrated knowledge translation (IKT) approach. We conducted a four-phase mixed-methods study including: (1) translating and piloting Spanish-PROACTIVE in 22 centers across 12 countries in Latin America and Spain, (2) identifying institutional and regional pediatric onco-critical care challenges and QI priorities, (3) assessing barriers to disseminating results, and (4) co-developing dissemination tools. The professionally translated and refined Spanish-PROACTIVE identified key institutional and common regional pediatric onco-critical care challenges including lack of multidisciplinary rounds (only 14% availability). Institutional barriers to disseminating results included limited time and resources, gaps in dissemination knowledge and skill, and lack of mentorship. These findings informed the co-development of tailored dissemination tools, including a leadership-focused slide deck and a clinical-staff-targeted infographic to support internal dissemination. Applying an IKT approach effectively addressed language and dissemination barriers, and improved accessibility and local relevance of PROACTIVE. Spanish-PROACTIVE supports consistent multilingual data collection, and its contextually tailored dissemination tools may enhance internal communication and uptake of findings across Spanish-speaking institutions. This approach offers a practical model for strengthening dissemination and accelerating uptake of intervention results in linguistically diverse, resource-constrained settings, supporting global efforts to improve outcomes for children with cancer.
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