Evidence map›Paper›PMID 42077290›Full record

ReviewFrontiers in psychology2026

Challenging the prescientific frameworks of criminal justice: neurobiology and criminolytic interventions in the legalome era.

Alan C Logan, Pragya Mishra, Colleen M Berryessa, Gregg D Caruso, Fiona A Hagenbeek, Thomas F Denson, Jake M Robinson, Susan L Prescott

Abstract readReview
In one paragraph

Review in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alan C LoganCenter for Justice and Mental Well-being, Nova Institute for Health, Baltimore, MD, United States.
Pragya MishraDepartment of Law, University of Allahabad, Prayagraj, India.
Colleen M BerryessaSchool of Criminal Justice, Rutgers University, Newark, NJ, United States.
Gregg D CarusoSchool of Business, Fairfield University, Fairfield, CT, United States.
Fiona A HagenbeekDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Thomas F DensonSchool of Psychology, University of New South Wales, Sydney, NSW, Australia.
Jake M RobinsonCollege of Science and Engineering, Flinders University, Bedford Park, SA, Australia.
Susan L PrescottCenter for Justice and Mental Well-being, Nova Institute for Health, Baltimore, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contemporary systems of criminal justice are rooted in prescientific folk psychology assumptions related to moral fiber, free will, agency, and near-universal levels of willpower. For instance, people often believe that morally "defective" people make voluntary choices, failing to utilize their own self-control capacities. Given the wide acceptance of such beliefs, they are considered "normative" within law, serving to underpin retributive punishment. However, rapid advances in biological sciences-aided by multi-omics technologies-have illuminated the ways in which brain architecture and current metabolic conditions can constrain agency and shape here-and-now decision-making. Here in this perspective article, we examine how these advances are placing the prescientific foundations of criminal justice systems under duress. Older single-gene and single neuroimage attempts at explaining criminal behavior are giving way to the legalome era. This describes a more holistic epoch in which the simultaneous integration of mass biological data (e.g., polygenetic, metabolic, microbiome, metabolomic, lipidomic, and other omics-derived information) can provide explanatory power to criminal behavior and vulnerability, and guide personalized approaches to prevention and treatment. Advances in behavioral epigenetics are revealing how genetic predispositions interact with the exposome to shape human behavior through dynamic, potentially modifiable mechanisms. Moreover, evidence suggests that the human microbiome acts as a dynamic interface between environment and brain, influencing behavior in ways that are relevant to vulnerability, impulse control, and decision-making. Promising criminolytic interventions range from nutritional and pharmaceutical approaches to cognitive-behavioral therapy and contemplative practices. The integration of biological evidence and science education, along with ethically guided neurointerventions, will be critical to more humane systems of judgement.

Indexed as

auto-brewery syndromebehavioral epigeneticsbiological criminologyhologenomelegalomemicrobiomeneuroethicsrehabilitation

Identifiers

PMID42077290
PMCPMC13128424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.