ArticleFrontiers in endocrinology2026
Linear associations of triglyceride-glucose body mass index and atherogenic index of plasma with the risk of diabetes: a retrospective cohort study.
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This research intends to examine the relationship between triglyceride glucose-body mass index (TyG-BMI) and the Atherogenic Index of Plasma (AIP) in relation to the risk of diabetes, as well as evaluate their predictive capabilities. Methods: This retrospective cohort study included data from 116,662 Chinese adults with normal baseline glucose levels. Participants were categorized according to tertiles of triglyceride-glucose body mass index (TyG-BMI; TT1-TT3) and atherogenic index of plasma (AIP; TA1-TA3), as well as nine combined categories (TC1-TC9). Incident diabetes mellitus (DM) was assessed after a mean follow-up of 37.4 months, and the primary endpoint was new-onset DM. Results: The overall incidence of DM was 2.3% (n = 2,681). After adjustment for covariates, both TyG-BMI and AIP were independent risk factors for DM (TyG-BMI: OR = 1.0100, Conclusions: In this Chinese adult cohort, TyG-BMI and AIP were significantly associated with incident DM and showed added predictive value. Incorporating TyG-BMI, AIP, or their combination into the baseline risk model significantly improved diabetes risk prediction.
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