Evidence mapPaperPMID 42077461Full record

ReviewFrontiers in endocrinology2026

Faecal microbiota transplantation and glucolipid metabolic disorders: the interventional role of gut microbiota.

Jiali Wu, Yusheng Qiu, Jiaying Deng, Yangpeng Li, Biao Jia, Zheng Cao, Jiaqing Tao, Jiao Guo

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiali Wu *Guangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Yusheng Qiu *Guangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Jiaying Deng *Guangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Yangpeng Li *Guangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Biao JiaGuangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Zheng CaoGuangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Jiaqing TaoGuangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
Jiao GuoGuangdong Metabolic Diseases Research Centre of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education; Guangdong Traditional Chinese Medicine Key Laboratory for Metabolic Diseases, Guangzhou Higher Education Mega Centre, Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucolipid metabolic disorders (GLMD) have emerged as a significant global public health issue, posing a significant threat to human health. With changes in modern social structures and an ageing population, the incidence of GLMD is on the rise and is increasingly affecting younger populations. Faecal microbiota transplantation (FMT) directly modifies the gut microbiota to reestablish its equilibrium and metabolites, consequently reinstating gut barrier integrity, mitigating chronic low-grade inflammation, and affecting the onset and progression of GLMD through the regulation of the gut-liver axis. This paper reviews the application of FMT in the treatment of GLMD, emphasizing research outcomes and efficacy assessments in clinical trials and animal studies. As a simple and secure intervention, FMT is anticipated to provide new therapeutic alternatives for GLMD patients in the future with the deepening of relevant research, the screening of specific probiotics and the revelation of functional mechanisms. This paper aims to clarify the potential mechanism of FMT in addressing GLMD, summarise recent research developments in this field, and anticipate the opportunities and challenges of FMT in clinical application.

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeMetabolic DiseasesAnimalsHumansIntestinal Barrier Functionfaecal microbiota transplantationglucolipid metabolic disorders (GLMD)gut microbiotaintestinal barriermetabolic syndrome

Identifiers

PMID42077461
PMCPMC13128379

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.