Regressive Neuroblastoma: Widely Accepted, Underreported Histology.

Tom Membrez, Jim C H Wilde, Oliver Sanchez, Danai Papangelopoulou, Fabienne Gumy-Pause, Anne-Laure Rougemont

Abstract read

In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tom MembrezPediatric and Fetoplacental Pathology Unit, Division of Clinical Pathology, Diagnostic Department Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.

Jim C H WildeDivision of Pediatric Surgery, Department of Women, Child and Adolescent Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.

Oliver SanchezDivision of Pediatric Surgery, Department of Women, Child and Adolescent Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.

Danai PapangelopoulouDivision of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.

Fabienne Gumy-PauseDivision of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.

Anne-Laure RougemontPediatric and Fetoplacental Pathology Unit, Division of Clinical Pathology, Diagnostic Department Geneva University Hospitals and Faculty of Medicine, University of Geneva Geneva Switzerland.ORCID https://orcid.org/0000-0002-1785-792X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroblastoma accounts for approximately 8% of all pediatric cancers and up to 15% of pediatric cancer-related deaths in malignant cases; neuroblastoma is the most common malignancy in infancy. Notably, up to 50% of tumors may undergo spontaneous regression without treatment. However, detailed histological descriptions of regressed neuroblastoma remain limited in the literature. We report the histological features of a particularly illustrative case, characterized by edema, mild collagen deposition, evidence of prior hemorrhage, and calcifications. Cellularity was minimal, consisting of rare, scattered mature-appearing ganglion cells, without neuropil or neuroblastic clusters. Accurate recognition of these morphological features in surgical specimens is essential for optimal treatment planning.

Indexed as

differentiationfibrosismaturationmature ganglion cellsregressed neuroblastomaspontaneous regression

Identifiers

PMID42078043

DOI10.1002/ccr3.72640

PMCPMC13128518

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.