ArticleCurrent medicinal chemistry2026
Quantum Consciousness: A Molecular Perspective Involving Glycoprotein-Tunnelling Hypothesis (GPTH).
Article in Current medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Long-term memory exhibits a remarkable problem: it is extraordinarily stable over decades, yet it supports rapid, flexible cognition, logic, and conscious awareness. Classical neuroscience has largely attributed memory to synaptic plasticity and networklevel dynamics; however, these mechanisms alone do not adequately explain the molecular durability of memory traces in the face of continuous protein turnover. A hypothesis advanced by the author proposes that memory is encoded in stable, folded glycoprotein patterns, particularly within synaptic and peri-synaptic environments. This review examines how such structurally persistent molecular architectures could support dynamic information processing through quantum-enabled chemical mechanisms. Considering recent advances in glycobiology, enzymology, quantum biology, and medicinal chemistry, it is suggested that proton and electron tunnelling provide a plausible and experimentally grounded mechanism for reading out stable glycoprotein-encoded information without requiring large-scale molecular rearrangement or long-lived macroscopic quantum coherence. Such an approach reconciles molecular stability with cognitive flexibility and yields testable predictions that are relevant to neurodegenerative disease and drug discovery.
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