Evidence map›Paper›PMID 42084569›Full record

ArticleJACC. Case reports2026

Pediatric Pulmonary Hypertension: A Systematic Approach.

Andrew Corson, Ranjit Philip, Neil Tailor, Abhishek Chakraborty, Kaitlynn Littleford, Grace McCormick, Aaron Walsh

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrew CorsonDivision of Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA. Electronic address: acorson@uthsc.edu.
Ranjit PhilipDivision of Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Neil TailorDivision of Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Abhishek ChakrabortyDivision of Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Kaitlynn LittlefordThe University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USA.
Grace McCormickDepartment of Nutrition Therapy, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Aaron WalshDivision of Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA. Electronic address: awalsh8@uthsc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric pulmonary hypertension comprises a variety of etiologies across different age groups, requiring a systematic approach to diagnosis in children. CASE SUMMARY: A 7-year-old boy with nonverbal autism, oral aversion, and resolved muscular ventricular septal defect presented with heart failure and was found to have severe pulmonary hypertension. The initial diagnosis and treatment course was altered after a misleading cause, and he was ultimately found to have undetectable vitamin C levels. After repletion, he was weaned off pulmonary hypertension therapy and received nutritional supplementation via a gastrotomy tube. DISCUSSION: Chronic vitamin C deficiency can lead to pulmonary hypertension, and pediatric patients with neurodevelopmental disorders are at a higher risk of developing nutritional deficiencies. TAKE-HOME MESSAGE: This case emphasizes the importance of having a broad differential for pulmonary hypertension, with a systematic approach to thinking beyond congenital heart disease-related, autoimmune-related, and idiopathic pulmonary hypertension in children.

Indexed as

autism spectrum disordercongenital heart defectdietechocardiographymalnutritionpulmonary hypertensionright ventriclethrombosisthrombus

Identifiers

PMID42084569
PMCPMC13261851

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.