Evidence mapPaperPMID 42084797Full record

Trial reportJournal of the International Society of Sports Nutrition2026

Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.

Seyed Morteza Tayebi, Meraj Mirzaei, Jeffrey R Stout

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seyed Morteza TayebiDepartment of Exercise Physiology, Faculty of Sports Science, Allameh Tabataba'i University, Tehran, Iran.ORCID 0000-0003-0459-4443
Meraj MirzaeiDepartment of Exercise Physiology, Faculty of Sports Science, Allameh Tabataba'i University, Tehran, Iran.ORCID 0009-0007-0591-6180
Jeffrey R StoutUniversity of Central Florida, School of Kinesiology and Rehabilitation Sciences, Orlando, FL, USA.ORCID 0000-0001-6114-1649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHigh-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery. This randomized, double-blind, placebo-controlled pilot trial examined whether acute

methodsTwenty-two male elite judoka were randomized to HMB-FA (1.0 g BetaTOR®) or placebo. Supplements were ingested after four simulated Olympic judo bouts. Blood was sampled pre-exercise, post-fourth bout, and 2 h post-bout for creatine kinase (CK), lactate dehydrogenase (LDH), catalase (CAT), glutathione peroxidase (GPX), superoxide dismutase (SOD), malondialdehyde (MDA), and total antioxidant capacity (TAC). Twenty-one completed the protocol (one placebo dropout due to injury). Data were analyzed via 2 × 3 mixed ANOVA with partial

resultsNo group differences were seen for CK, MDA, or TAC (

conclusionAcute post-exercise HMB-FA supplementation in elite judo athletes did not significantly influence muscle damage or oxidative stress markers but transiently increased antioxidant enzyme activities (CAT, GPX, and SOD). These findings suggest an enzyme-specific effect and highlight the need for future studies using more precise oxidative-stress markers and cellular assays to better evaluate antioxidant responses; however, these effects should be interpreted with caution due to potential limitations related to assay sensitivity and the timing of measurements.

Indexed as

AntioxidantsDietary SupplementsMartial ArtsMuscle, SkeletalOxidative StressValeratesBiomarkersCatalaseCreatine KinaseDouble-Blind MethodGlutathione PeroxidaseHumansL-Lactate DehydrogenaseMaleMalondialdehydePilot ProjectsAntioxidantsbeta-hydroxyisovaleric acidBiomarkersCatalaseCreatine KinaseGlutathione PeroxidaseL-Lactate DehydrogenaseMalondialdehydeSuperoxide DismutaseValeratesBeta-hydroxy-beta-methylbutyrate free acidelite athletesmuscle recoveryoxidative stressperformancesimulated olympic competition

Identifiers

PMID42084797
PMCPMC13148084

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.