Evidence map›Paper›PMID 42087044›Full record

SynthesisCanadian journal of anaesthesia = Journal canadien d'anesthesie2026

Glucagon-like peptide-1 receptor agonists and gastric emptying time: a systematic review and meta-analysis of prospective studies.

Alisia Chen, Karen Zhao, Felicia Ceban, Majid Nabipoor, Marina Englesakis, Frances Chung, Anahi Perlas

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alisia ChenDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Karen ZhaoDepartment of Family Medicine, University of Toronto, Toronto, ON, Canada.
Felicia CebanMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Majid NabipoorBiostatistics Department, University Health Network, Toronto, ON, Canada.
Marina EnglesakisLibrary & Information Services, University Health Network, Toronto, ON, Canada.
Frances ChungDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
Anahi PerlasDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, Toronto, ON, Canada. Anahi.perlas@uhn.ca.ORCID http://orcid.org/0000-0002-8190-8314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCurrent management of type 2 diabetes mellitus and obesity increasingly includes treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs). In this systematic review and meta-analysis, we sought to characterize the effect of GLP-1 RAs on gastric emptying half-time (T

methodsWe conducted a systematic review of prospective studies reporting T

resultsWe included 10 studies (N = 300), one of which reported two independent samples; these were treated as two independent studies for the purpose of meta-analysis. Glucagon-like peptide-1 receptor agonists significantly increased gastric emptying T

conclusionsIn this systematic review and meta-analysis, we found that GLP-1 RAs significantly prolonged gastric emptying T STUDY REGISTRATION: PROSPERO ( CRD42023461665 ); first submitted 8 September 2023.

Indexed as

Diabetes Mellitus, Type 2Gastric EmptyingGlucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsObesityHumansProspective StudiesRandomized Controlled Trials as TopicTime FactorsGlucagon-Like Peptide-1 Receptor AgonistsHypoglycemic Agentsgastric emptyinggastric emptying timeGLP-1 RAsglucagon-like peptide-1 receptor agonistsmeta-analysis

Identifiers

PMID42087044
PMCPMC13249630

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.