Evidence map›Paper›PMID 42087097›Full record

ArticleBMC neurology2026

A case of CD36 deficiency with multiple white matter lesions.

Yuta Kizuka, Hiroyuki Yamakawa, Yu Iwabuchi, Jun Sakai, Chika Terayama, Yoko Yatabe, Tomoko Arai, Hiromichi Matsushita, Masaki Ieda, Jin Nakahara and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuta KizukaDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Hiroyuki YamakawaDepartment of Cardiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Yu IwabuchiDepartment of Radiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Jun SakaiDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Chika TerayamaDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Yoko YatabeDepartment of Clinical Laboratory, Keio University Hospital, 160-8582, Tokyo, Japan.
Tomoko AraiDepartment of Clinical Laboratory, Keio University Hospital, 160-8582, Tokyo, Japan.
Hiromichi MatsushitaDepartment of Laboratory Medicine, Keio University School of Medicine, Tokyo, 160- 8582, Japan.
Masaki IedaDepartment of Cardiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Jin NakaharaDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
Yoshikane IzawaDepartment of Neurology, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan. y-izawa.a3@keio.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD36 deficiency is associated with abnormal fatty acid metabolism, which may increase the risk of developing atherosclerosis. However, there are few reports on a possible link between CD36 deficiency and cerebral white matter lesions. CASE REPORT: We present the case of a 44-year-old woman with heart failure due to CD36 deficiency and multiple white matter lesions. Her comprehensive examination for heart failure, including a single-photon emission computed tomography (SPECT) with

conclusionThis case suggests a potential association between CD36 deficiency and cerebral small-vessel disease. Further studies in patient cohorts with CD36 deficiency are warranted to clarify the impact of this condition on cerebral microcirculation.

Indexed as

CD36 AntigensLeukoencephalopathiesWhite MatterAdultFemaleHeart FailureHumansMagnetic Resonance ImagingTomography, Emission-Computed, Single-PhotonCD36 AntigensCD36 protein, humanCD36 deficiencyHeart failureWhite matter lesions

Identifiers

PMID42087097
PMCPMC13289481

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.