Trial reportJournal of cosmetic dermatology2026
Efficacy and Safety of a Dual-Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split-Face Randomized Controlled Trial.
Trial report in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe 589/1319 nm solid-state dual-wavelength (SSDW) laser, which targets cutaneous vasculature, may be an effective treatment for acne erythema (AE).
objectivesTo compare the efficacy and safety of the 589/1319 nm SSDW laser with topical soothing Aloe vera (AV) gel for the treatment of AE. PATIENTS AND
methodsThirty patients with bilateral AE were enrolled. One facial side received 6 sessions of 589/1319 nm SSDW laser treatment, while the contralateral side was treated with twice-daily AV gel for 18 weeks. Patients were followed for 8 weeks after the final laser session. AE severity, acne severity, and adverse events were assessed.
resultsTwenty-nine patients completed the study. Both treatment modalities significantly reduced AE. The laser-treated side demonstrated a faster clinical response, with a significant reduction compared to baseline at 2 weeks, whereas AV gel required 4 weeks to achieve a comparable effect (within-group p < 0.05; no between-group difference). At the 8-week follow-up, the response rate was 72% for the laser-treated sides and 69% for the AV-treated sides. AE improvement correlated with reductions in acne severity in the laser-treated sides (r
conclusionsThe 589/1319 nm SSDW laser may be an effective early adjunctive treatment for acne erythema, offering minimal discomfort with no downtime and may additionally improve acne severity.
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