Metformin × all-cause mortality

SynthesisFrontiers in endocrinology2026

Association of preadmission metformin use and prognosis in patients with sepsis with diabetes: a systematic review and meta-analysis.

Mingying Zhang et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer deaths

−42%−56% to −25%

Bigger than 9 in 10 for all-cause mortality

As reported

OR 0.58, 95% CI 0.44–0.75 · the paper's word: All-cause mortality

One number in the abstract

the abstract, start to end

with reduced overall mortality (OR 0.58, 95% CI 0.44-0.75, P <

← favours treatmentfavours comparator →
could be chance
All-cause mortality
OR 0.580.44–0.75
MetforminAll-cause mortality
1 / 3

Not cited yet

Full record →Abstract, authors, funding and every citing paper · PMID 42087873