ArticleFrontiers in nutrition2026
Synergistic enrichment and catalytic sensing platform based on ZIF-8-NH₂/dynamic Schiff base hydrogel for ultrasensitive detection of hydroquinone.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The development of sensing interfaces that can simultaneously achieve efficient enrichment of targets and enhanced electron conduction is the key to improving the performance of phenolics detection in food. Methods: In this paper, a novel electrochemical sensing platform consisting of an aminated zeolite imidazolium ester backbone material (ZIF-8-NH2) composited with sodium oxidized alginate (OSA)/carboxymethyl chitosan (CMCS) dynamic hydrogel (denoted as OC hydrogel) was successfully constructed. The platform exploits the mild Schiff base reaction between OSA and CMCS to construct a three-dimensional dynamic hydrogel substrate without an external cross-linking agent. On this basis, the combination of ZIF-8-NH2 and OC hydrogel was introduced. The amino groups on the surface of ZF-8-NH2 and the aldehyde groups of OSA are utilized to form covalent nano-crosslinking points, simultaneously exerting their electrocatalytic activity and pre-enrichment effect. Results: Electrochemical studies demonstrated that the composite interface significantly accelerated electron transfer kinetics. The constructed sensor demonstrates exceptional analytical performance for hydroquinone. The detection limit is as low as the nanomolar level (16.7 nM), and the linear range extends up to four orders of magnitude (0.05 to 1800 μM). Furthermore, the sensor demonstrated its efficacy in the rapid analysis of a wide range of real samples (tap water, drinking water, beverages, and vegetable juices), with recoveries ranging from 97.4 to 103.6%. Discussion: The observed performance is attributed to the multiple synergistic effects of the ZIF-8-NH2/OC hydrogel interface. The covalent connection between ZIF-8-NH2 and the OSA/CMCS hydrogel prevents nanomaterial detachment, ensuring interface stability. Meanwhile, ZIF-8-NH₂ reduces the overpotential for hydroquinone electrochemical oxidation and achieves significant signal amplification through pre-enrichment of target molecules. These features substantiate the reliability of the sensor in practical applications, offering an innovative solution for the detection of harmful substances in food.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.