Evidence map›Paper›PMID 42088407›Full record

ArticleFrontiers in toxicology2026

Examining

Kostja Renko, Ryne Thomas, MaryAnn Hawks, Jermaine Ford, Josef Köhrle, Marta Axelstad, Mary E Gilbert

Abstract read
In one paragraph

Article in Frontiers in toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kostja RenkoBFR German Federal Institute for Risk Assessment, German Centre for the Protection of Laboratory Animals (Bf3R), Berlin, Germany.
Ryne ThomasOffice of Research and Development, Environmental Protection Agency, Research Triangle Park, Durham, NC, United States.
MaryAnn HawksOffice of Research and Development, Environmental Protection Agency, Research Triangle Park, Durham, NC, United States.
Jermaine FordOffice of Research and Development, Environmental Protection Agency, Research Triangle Park, Durham, NC, United States.
Josef KöhrleCharité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institut für Experimentelle Endokrinologie, Berlin, Germany.
Marta AxelstadNational Food Institute, Technical University of Denmark, Lyngby, Denmark.
Mary E GilbertOffice of Research and Development, Environmental Protection Agency, Research Triangle Park, Durham, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormone (TH) availability is particularly critical for early brain development. TH transport across the blood-brain barrier is facilitated through two main transmembrane transporters: monocarboxylate transporter 8 (MCT8) and organic anion transporter 1C1 (OATP1C1). Inhibition of MCT8-mediated TH transport has been identified for a number of environmental chemicals using

Indexed as

dehalogenasedeiodinasein vivoMct8silybinsilychristinthyroid hormonethyroid hormone transmembrane transporter

Identifiers

PMID42088407
PMCPMC13138798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.