Evidence map›Paper›PMID 42088807›Full record

ArticleCureus2026

Recurrence Rate and Risk Factors for Apical Prolapse After Sacrospinous Ligament Fixation: A Prospective Cohort Study.

Musa Kayondo, Rogers Kajabwangu, Onesmus Byamukama, Brenda Ainomugisha, Kalyebara Paul Kato, Leevan Tibaijuka, Henry M Lugobe, Verena Geissbuehler

Abstract read
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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Musa KayondoObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Rogers KajabwanguObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Onesmus ByamukamaObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Brenda AinomugishaObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Kalyebara Paul KatoObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Leevan TibaijukaObstetrics and Gynecology, Mbarara University of Science and Technology, Mbarara, UGA.
Henry M LugobeObstetrics and Gynaecology, Mbarara University of Science and Technology, Mbarara, UGA.
Verena GeissbuehlerObstetrics and Gynaecology, University of Basel, Basel, CHE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to determine the one-year recurrence rate of apical prolapse following sacrospinous ligament fixation and to identify clinical and surgical risk factors associated with recurrence in a low-resource setting.

methodsThis was a prospective cohort study of women who underwent sacrospinous ligament fixation as part of surgery for apical prolapse at the urogynecology unit of Mbarara Regional Referral Hospital (MRRH) in Uganda. The surgeries performed included vaginal hysterectomy with sacrospinous ligament vault fixation, sacrospinous ligament hysteropexy, and sacrospinous ligament vault fixation for those with post-hysterectomy vaginal vault prolapse. Concomitant procedures such as anterior or posterior repair, or both, were performed for women with prolapse in other compartments. The women were followed up for a period of one year post-surgery. Recurrence was assessed with the women in lithotomy position under maximum strain using the Pelvic Organ Quantification (POP-Q) system. Recurrence was defined as apical prolapse of ≥POP-Q stage II. Multivariable log-binomial regression was performed to determine risk factors for recurrence.

resultsA total of 123 participants were enrolled in this study, of which 111 (90.2%) completed follow-up. The mean age was 53.1 (SD ±13.6) years. The majority of apical prolapse was uterine (94.6%) and classified as POP-Q stage III (58.6%). The recurrence rate was 19.8% (22/111, 95% CI: 13.4-28.4). Risk factors for apical prolapse recurrence included body mass index (BMI) >25 kg/m

conclusionsApical prolapse recurrence after sacrospinous ligament fixation is common in this setting. To reduce the risk of recurrence, management protocols should prioritize prevention and timely management of postoperative complications, and counseling for weight optimization. Furthermore, vaginal hysterectomy should be considered in uterine prolapse where uterine sparing surgery is not required.

Indexed as

apical prolapserecurrencerisk factorssacrospinous ligament fixationuganda

Identifiers

PMID42088807
PMCPMC13137387

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.