Evidence map›Paper›PMID 42088821›Full record

ArticleCureus2026

Chronic Inflammatory Demyelinating Polyneuropathy in a Patient With Autoimmune Autonomic Ganglionopathy: A Case Report.

Emily N Taylor, Jason E Hansen, Justin White

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily N TaylorDepartment of Medicine, University of New England College of Osteopathic Medicine, Portland, USA.
Jason E HansenDepartment of Medicine, University of New England College of Osteopathic Medicine, Portland, USA.
Justin WhiteDepartment of Hospital Medicine, Northern Light AR Gould Hospital, Presque Isle, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case describes a 61-year-old woman with autoimmune autonomic ganglionopathy (AAG) on long-term intravenous immunoglobulin (IVIG) who developed progressive weakness and sensory loss, ultimately diagnosed as chronic inflammatory demyelinating polyneuropathy (CIDP). Initially evaluated for Guillain-Barré syndrome, cerebrospinal fluid analysis revealed albuminocytologic dissociation without central lesions on MRI. Despite IVIG therapy, symptoms worsened, and electrodiagnostic testing demonstrated demyelination with conduction block and secondary axonal loss, confirming CIDP. Subsequent plasma exchange therapy led to gradual improvement in strength, reflexes, and ambulation while autonomic function remained stable. The coexistence of CIDP and AAG is exceedingly rare and emphasizes the potential for shared autoimmune mechanisms within the peripheral nervous system. This case highlights the importance of recognizing overlapping autoimmune neuropathies, particularly when new or progressive symptoms arise despite appropriate therapy and adapting immunomodulatory treatment accordingly to optimize long-term outcomes.

Indexed as

autoimmune autonomic ganglionopathyautoimmune illnessautoimmune inflammatory demyelinating polyneuropathychronic inflammatory demyelinating polyneuropathy (cidp)guillain-barre syndrome (gbs)

Identifiers

PMID42088821
PMCPMC13138858

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.