Evidence map›Paper›PMID 42090367›Full record

ArticlePloS one2026

Prevalence and determinants of parental refusal of human papillomavirus vaccination in Morocco: A multicenter cross-sectional study.

Touria Essayagh, Meriem Essayagh, Kaoutar Nmila, Housnia Slibani, Soukayna El Hachimi, Mustapha El Boukhari, Hajar Lemriss, Sanaâ Lemriss, Rehmatullah Zadran, Halima Tigaidi and 1 more

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Touria EssayaghHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Meriem EssayaghOffice National de Sécurité Sanitaire des produits Alimentaires, Meknès, Morocco.
Kaoutar NmilaHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Housnia SlibaniHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Soukayna El HachimiHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Mustapha El BoukhariHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Hajar LemrissHassan First University of Settat, Institut Supérieur des Sciences de la Santé, Laboratoire des Sciences et ingénierie biomédicales, biophysique et santé, Settat, Morocco.
Sanaâ LemrissLaboratoire of Research and Medical Analysis of Gendarmerie Royale, Department of Biosafety, Rabat, Morocco.
Rehmatullah ZadranNational Infectious Diseases Hospital Laboratory, Kabul, Afghanistan.ORCID https://orcid.org/0009-0000-4603-620X
Halima TigaidiUniversity of Kordofan, Faculty of Public and environmental Health, Elobeid, Sudan.
Sanah EssayaghHassan First University of Settat, Faculté des Sciences et Techniques, Laboratoire Agroalimentaire et Santé, Settat, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVaccination against the human papillomavirus (HPV) is an effective way to avert cervical cancer. However, acceptance in Morocco remains inadequate. The aim of this study was to measure the prevalence of parental HPV vaccine refusal and the risk factors associated with it.

methodsBetween 3 March and 30 September 2025, a multicenter cross-sectional survey was conducted among Moroccan parents of girls aged 11-14 who attended health facilities. The study looked at sociodemographic factors, knowledge regarding HPV and cervical cancer, and vaccination attitudes. A multivariate logistic regression analysis was used to identify risk factors for vaccination refusal.

resultsThe research included 1,444 participants with an average age of 37.7 ± 6.6 years. Of them, 415 refused HPV vaccination for their daughters, resulting in a prevalence of 28.7%. Vaccine refusal was substantially related to higher educational levels, lower income, less faith in the healthcare system, less knowledge about cervical cancer and its symptoms, and insufficient information regarding the HPV vaccine as seen by the media. Refusal was also associated with a poor perception of the seriousness of HPV infection, fear of vaccinating daughters, noncompliance with past vaccination schedules, difficulties accessing health centers, and a lack of recommendations from healthcare professionals. In contrast, refusal was inversely associated with parents who were uninformed of the proper number of vaccination doses or uninformed regarding the availability of the HPV vaccine at health centers or who feared the vaccine may cause an adverse reaction.

conclusionParental refusal of HPV vaccination is still a substantial obstacle. To increase acceptability and enhance cervical cancer prevention in Morocco, it is critical to expand communication strategy, boost public knowledge, and assure active participation of healthcare professionals.

Indexed as

Human Papillomavirus VirusesPapillomavirus InfectionsPapillomavirus VaccinesParentsUterine Cervical NeoplasmsVaccinationVaccination RefusalAdolescentAdultChildCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansMiddle AgedMoroccoPapillomavirus Vaccines

Identifiers

PMID42090367
PMCPMC13148701

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.