Evidence map›Paper›PMID 42093621›Full record

ArticleVirulence2026

Neutralizing epitope mapping for deltacoronavirus receptor-binding domain and seroepidemiological survey across different animal species.

Dexin Li, Liying Hao, Baicheng Huang, Zhiyan Wang, Zenglin Wang, Menghao Guo, Yunjing Zhang, Junhua Deng, Yufang Li, Shaoruo Zhao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dexin LiJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Liying HaoLuoyang Putai Biotechnology Co. Ltd, Luoyang, China.
Baicheng HuangZhejiang Lab, Hangzhou, Zhejiang, China.
Zhiyan WangLuoyang Putai Biotechnology Co. Ltd, Luoyang, China.
Zenglin WangJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Menghao GuoZhejiang Lab, Hangzhou, Zhejiang, China.
Yunjing ZhangNational Research Center for Veterinary Medicine, Luoyang, China.
Junhua DengLuoyang Putai Biotechnology Co. Ltd, Luoyang, China.
Yufang LiLuoyang Putai Biotechnology Co. Ltd, Luoyang, China.
Shaoruo ZhaoLuoyang Putai Biotechnology Co. Ltd, Luoyang, China.
Kegong TianNational Research Center for Veterinary Medicine, Luoyang, China.
Xiangdong LiJiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.ORCID 0000-0002-4635-1602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that poses a significant threat to the global swine industry and carries a potential public health risk. The development of neutralizing monoclonal antibodies (mAbs) is crucial for preventing and controlling PDCoV. However, research on neutralizing linear epitopes within the PDCoV receptor-binding domain (RBD) and the establishment of serological assays based on such mAbs remains limited. In this study, we generated two neutralizing mAbs, 1C12 and 3A11, targeting the PDCoV RBD. Epitope mapping revealed that 1C12 recognizes a linear epitope (

Indexed as

Antibodies, NeutralizingCoronavirus InfectionsDeltacoronavirusEpitope MappingReceptors, VirusSwine DiseasesAnimalsAntibodies, MonoclonalAntibodies, ViralEnzyme-Linked Immunosorbent AssayEpitopesNeutralization TestsSeroepidemiologic StudiesSwineAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralEpitopesReceptors, Virusblocking ELISAmonoclonal antibodyneutralizing epitopePorcine deltacoronavirus

Identifiers

PMID42093621
PMCPMC13166184

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.