ArticleFrontiers in cardiovascular medicine2026
Development and validation of a risk prediction model for myocardial hypoperfusion after primary PCI in ST-segment elevation myocardial infarction.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To analyze the determinants of myocardial hypoperfusion following primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) and to develop a risk prediction model. Methods: Clinical data from 434 patients with STEMI who underwent primary PCI at our hospital between January 2023 and June 2025 were retrospectively collected. Patients were randomly assigned to a training cohort ( Results: Multivariable logistic regression identified time from onset to primary PCI, atorvastatin dose before PCI, balloon deflation method during PCI, red cell distribution width (RDW), and monoamine oxidase (MAO) levels as independent predictors of myocardial hypoperfusion (all Conclusion: Time from onset to primary PCI, atorvastatin dose before PCI, balloon deflation method during PCI, RDW, and MAO levels are important determinants of myocardial hypoperfusion following primary PCI in patients with STEMI. The proposed prediction model demonstrated favorable predictive performance and clinical utility, suggesting its potential value for early risk stratification.
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