ArticleScientific reports2026
Association of C-reactive protein to albumin ratio with the risk of left ventricular aneurysm formation.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Development and validation of an interpretable machine learning model for predicting atrial fibrillation risk in middle-aged and older patients with coronary heart disease.Frontiers in cardiovascular medicine · 2026Article
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Authors and funding
10 authors.
Funding
Abstract
The C-reactive protein (CRP) to albumin ratio (CAR) has emerged as a novel marker of inflammation. However, its potential predictive value for the development of left ventricular aneurysm (LVA) has not yet been evaluated. This study aims to explore the association between CAR and the risk of LVA in patients experiencing acute ST-segment elevation myocardial infarction (STEMI). This study recruited 551 patients in the first cohort and 471 patients in the validation cohort. Multivariable logistic regression analysis, restricted cubic splines (RCS) analysis, and receiver operating characteristic were conducted to assess the predictive value of CAR for LVA. The prevalence of LVA were 14.5% in the first cohort and 13.6% in the validation cohort. Multivariable logistic regression analysis indicated that individuals in the highest quartile of CAR (Q4) were significantly associated with the risk of LVA formation compared to those in the lowest quartile (Q1) in both cohorts (First cohort: OR = 3.26, 95% CI = 1.51-7.05, P = 0.003; Validation cohort: OR = 4.05, 95% CI = 1.71-9.60, P = 0.002). RCS analysis demonstrated a positive and nonlinear association between CAR and the risk of LVA (overall P < 0.05, nonlinear P < 0.05). Furthermore, the discriminative ability of CAR for LVA is 0.72 in the first cohort and 0.74 in the validation cohort, exceeding that of both CRP and albumin alone. Subgroup analyses further corroborated the robustness of our findings. Elevated CAR was independently linked to an increased risk of LVA development in patients with STEMI who received primary PCI. This finding may hold considerable significance for clinical practice and could aid in the development of a personalized prevention strategy that incorporates the monitoring of CAR.
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