SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026
Photobiomodulation for the treatment and prevention of chemotherapy- and/or radiotherapy-induced oral mucositis in cancer patients: a systematic review and meta-analysis of randomized clinical trials published in the last six years.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically evaluate and update the evidence about photobiomodulation therapy (PBMT) as a therapy for the prevention and/or treatment of oral mucositis (OM) induced by antineoplastic therapies.
methodsThis systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A systematic literature search was conducted across PubMed, Web of Science, Scopus, and Embase as the primary databases. Additional searches were performed in the Virtual Health Library (VHL) and LILACS through the BIREME platform, as well as in Redalyc and the Wiley Online Library, covering the period from 2020 to 2026. Only randomized clinical trials published within the last six years investigating PBMT as a preventive or therapeutic intervention for oral mucositis (OM) in cancer patients receiving chemotherapy and/or radiotherapy were included.
resultsSeven studies comprising 329 patients were included. PBMT proved to be highly effective in the management of OM (RR 0.50, 95% CI 0.35-0.73). Moderate heterogeneity was observed across studies (I
conclusionEvidence from recent randomized clinical trials confirms that PBMT is highly effective for the management of oral mucositis, reducing its incidence and severity, improving quality of life and treatment adherence, and potentially lowering healthcare costs during cancer therapy.
Indexed as
Identifiers
42098536What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.